Multiple sclerosis [MS] is a major cause of neurological disability. It is characterized by damage throughout the brain and spinal cord, with loss of myelin and myelinating cells and damage to neurons and axons. MS is the most common neurological disease in young adults, affecting approximately two million people worldwide.
Currently there is no cure for MS. The standard treatment of MS involves disease-modifying drugs, which often work to alleviate the symptoms of MS, but not curing the underlying issues. However, these drugs carry adverse side effects and are ineffective in preventing disease progression in many MS patients.
Stem Cells Treat Multiple Sclerosis Symptoms
Today Multiple sclerosis is incurable, but stem-cell therapy might offer valuable therapeutic potential. Stem Cell therapy is currently demonstrating efficacy in treating patients with variable disease severity, with the best results in early-stage rapidly progressing MS patients with active CNS inflammation. Due to the urgency in treatment required of MS patients, all forms of stem cell therapy should be pursued.
A strong rationale for cell-based therapy in multiple sclerosis is based on the ability of stem cells of neural and mesenchymal origin to decrease neuro-inflammation, to enhance repair processes, andperhaps to participate directly in remyelination, repair of damaged neurons.
Mesenchymal stem cells (MSCs) are precursor cells, or cells that can be isolated from adipose tissues(fat), bone marrow,and umbilical cords.They are then culture-expanded to increase cell numbers up to 300 million, many times the volume of the original sample. This drastic increase in cell number ensures maximum effectiveness during treatment.